BDBM50258648 CHEMBL469134::N-hydroxy-5-(5-oxo-5-(4-phenylthiazol-2-ylamino)pentyl)isoxazole-3-carboxamide

SMILES ONC(=O)c1cc(CCCCC(=O)Nc2nc(cs2)-c2ccccc2)on1

InChI Key InChIKey=VETFNWHZDHZTFS-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50258648   

TargetHistone deacetylase 3(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50258648(N-hydroxy-5-(5-oxo-5-(4-phenylthiazol-2-ylamino)pe...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant HDAC3More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50258648(N-hydroxy-5-(5-oxo-5-(4-phenylthiazol-2-ylamino)pe...)
Affinity DataIC50: 68nMAssay Description:Inhibition of human recombinant HDAC6More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50258648(N-hydroxy-5-(5-oxo-5-(4-phenylthiazol-2-ylamino)pe...)
Affinity DataIC50: 254nMAssay Description:Inhibition of human recombinant HDAC10More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50258648(N-hydroxy-5-(5-oxo-5-(4-phenylthiazol-2-ylamino)pe...)
Affinity DataIC50: 303nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50258648(N-hydroxy-5-(5-oxo-5-(4-phenylthiazol-2-ylamino)pe...)
Affinity DataIC50: 430nMAssay Description:Inhibition of human recombinant HDAC2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed