BDBM50259283 CHEMBL466919::N-(8-(bis(2-chlorophenyl)methyl)-3-phenyl-8-azabicyclo[3.2.1]octan-3-yl)cyclopropanecarboxamide

SMILES Clc1ccccc1C(N1C2CCC1CC(C2)(NC(=O)C1CC1)c1ccccc1)c1ccccc1Cl

InChI Key InChIKey=IQKRJMYITRFRAP-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50259283   

TargetNociceptin receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50259283(CHEMBL466919 | N-(8-(bis(2-chlorophenyl)methyl)-3-...)
Affinity DataKi:  11nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human cloned NOP receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50259283(CHEMBL466919 | N-(8-(bis(2-chlorophenyl)methyl)-3-...)
Affinity DataKi:  996nMAssay Description:Displacement of [3H]diprenorphine from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50259283(CHEMBL466919 | N-(8-(bis(2-chlorophenyl)methyl)-3-...)
Affinity DataEC50:  35nMAssay Description:Agonist activity at human NOP assessed as stimulation of GDP-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed