BDBM50261762 (+/-)-exo-2-(3-methylisoxazol-5-yl)-7-aza-bicyclo[2.2.1]heptane::CHEMBL503604

SMILES Cc1cc(on1)[C@H]1C[C@H]2CC[C@H]1N2

InChI Key

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50261762   

LigandPNGBDBM50261762((+/-)-exo-2-(3-methylisoxazol-5-yl)-7-aza-bicyclo[...)
Affinity DataKi:  0.400nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50261762((+/-)-exo-2-(3-methylisoxazol-5-yl)-7-aza-bicyclo[...)
Affinity DataKi:  0.460nMAssay Description:Binding affinity to alpha4beta2 nAChRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50261762((+/-)-exo-2-(3-methylisoxazol-5-yl)-7-aza-bicyclo[...)
Affinity DataKi:  0.600nMAssay Description:Displacement of [3H]nicotine from alpha4beta2 nAChR in rat cerebral membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50261762((+/-)-exo-2-(3-methylisoxazol-5-yl)-7-aza-bicyclo[...)
Affinity DataKi:  1.33nMAssay Description:Displacement of [3H]cystisine from alpha4beta2 nAChRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50261762((+/-)-exo-2-(3-methylisoxazol-5-yl)-7-aza-bicyclo[...)
Affinity DataKi:  6nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7 nAChR in rat cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed