BDBM50262479 7-Phenyl-1-(pyridazin-3-yl)-heptan-1-one::CHEMBL455556

SMILES O=C(CCCCCCc1ccccc1)c1cccnn1

InChI Key InChIKey=DXGZKZUTNHLJNE-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50262479   

TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50262479(7-Phenyl-1-(pyridazin-3-yl)-heptan-1-one | CHEMBL4...)
Affinity DataKi:  140nMpH: 9.0Assay Description:Inhibition of rat FAAH expressed in Escherichia coli at pH 9.0More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50262479(7-Phenyl-1-(pyridazin-3-yl)-heptan-1-one | CHEMBL4...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of rat FAAH expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetLiver carboxylesterase 1(Human)
Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50262479(7-Phenyl-1-(pyridazin-3-yl)-heptan-1-one | CHEMBL4...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of TGHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50262479(7-Phenyl-1-(pyridazin-3-yl)-heptan-1-one | CHEMBL4...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of full-length human DAGLalpha expressed in HEK293T cell membranes using para-nitrophenylbutyrate by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetNeutral cholesterol ester hydrolase 1(Human)
Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50262479(7-Phenyl-1-(pyridazin-3-yl)-heptan-1-one | CHEMBL4...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of KIAA1363 hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed