BDBM50264191 CHEMBL492218::N-{(3-exo)-8-[(6-Fluoro-2-naphthyl)methyl]-8-azabicyclo[3.2.1]oct-3-yl}-2-pyridin-2-ylbenzamide

SMILES Fc1ccc2cc(CN3[C@@H]4CC[C@@H]3CC(C4)NC(=O)c3ccccc3-c3ccccn3)ccc2c1

InChI Key InChIKey=LMLBRLQIZFZLOQ-CLJLJLNGSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50264191   

TargetC-C chemokine receptor type 3(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50264191(CHEMBL492218 | N-{(3-exo)-8-[(6-Fluoro-2-naphthyl)...)
Affinity DataIC50:  57nMAssay Description:Antagonist activity at CCR3 receptor expressed in mouse B300-19 cells assessed as inhibition of eotaxin-induced calcium influx by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50264191(CHEMBL492218 | N-{(3-exo)-8-[(6-Fluoro-2-naphthyl)...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human CYP2D6 by fluorescence technique in presence of NADPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed