BDBM50265364 (S)-2-(6-(1-(2-hydroxy-3-methoxypropyl)-1H-pyrazol-4-yl)-2H-benzo[b][1,4]oxazin-4(3H)-yl)-6,6-dimethyl-6,7-dihydrothiazolo[5,4-c]pyridin-4(5H)-one::CHEMBL498002

SMILES COC[C@@H](O)Cn1cc(cn1)-c1ccc2OCCN(c3nc4CC(C)(C)NC(=O)c4s3)c2c1

InChI Key InChIKey=DDNDFDDGMCJGHM-INIZCTEOSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50265364   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL

LigandBDBM50265364((S)-2-(6-(1-(2-hydroxy-3-methoxypropyl)-1H-pyrazol...)Copy SMILESCopy InChI

Affinity DataIC50:  46nMAssay Description:Inhibition of PI3Kgamma (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL

LigandBDBM50265364((S)-2-(6-(1-(2-hydroxy-3-methoxypropyl)-1H-pyrazol...)Copy SMILESCopy InChI

Affinity DataIC50:  14nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI