BDBM50265440 3-(2-(1H-imidazol-1-yl)ethyl)-6-chloro-5-(1H-imidazol-1-yl)-2-methylquinoline::CHEMBL495565::NSC-666292

SMILES Cc1nc2ccc(Cl)c(-n3ccnc3)c2cc1CCn1ccnc1

InChI Key InChIKey=IYLACPJLCQDSFP-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50265440   

TargetAromatase(Human)
Universidade De Coimbra

Curated by ChEMBL
LigandPNGBDBM50265440(3-(2-(1H-imidazol-1-yl)ethyl)-6-chloro-5-(1H-imida...)
Affinity DataKi:  33.4nMAssay Description:Inhibition of human aromatase-mediated conversion of [1beta3H]androstenedione to estrone by Lineweaver-Burke plot in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAromatase(Human)
Universidade De Coimbra

Curated by ChEMBL
LigandPNGBDBM50265440(3-(2-(1H-imidazol-1-yl)ethyl)-6-chloro-5-(1H-imida...)
Affinity DataIC50: 96nMAssay Description:Inhibition of human aromatase-mediated conversion of [1beta3H]androstenedione to estrone by liquid scintillation counting in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed