BDBM50265521 2-(3-benzoylbenzofuran-5-yloxy)acetic acid::CHEMBL496153::cid_755496

SMILES OC(=O)COc1ccc2occ(C(=O)c3ccccc3)c2c1

InChI Key InChIKey=KBXOJEAZTMJGBZ-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50265521   

TargetGlycogen synthase kinase-3 beta(Human)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM50265521(cid_755496 | CHEMBL496153 | 2-(3-benzoylbenzofuran...)
Affinity DataEC50:  4.30E+3nMAssay Description:Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2011
Entry Details
PCBioAssay
TargetMacrophage migration inhibitory factor(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50265521(cid_755496 | CHEMBL496153 | 2-(3-benzoylbenzofuran...)
Affinity DataIC50: 9.80E+5nMAssay Description:Inhibition of human recombinant MIF tautomeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMacrophage migration inhibitory factor(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50265521(cid_755496 | CHEMBL496153 | 2-(3-benzoylbenzofuran...)
Affinity DataIC50: 1.50E+6nMAssay Description:Inhibition of human MIF-CD74 bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed