BDBM50267507 (R)-(3-(2-Fluoroethoxy)-2-methoxyphenyl)-(1-(2-p-fluorophenylethyl)-piperidine-4-yl)-methanol::CHEMBL515472
SMILES COc1c(OCCF)cccc1[C@H](O)C1CCN(CCc2ccc(F)cc2)CC1
InChI Key InChIKey=QCFZUTYIUYQTPW-JOCHJYFZSA-N
Data 26 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 26 hits for monomerid = 50267507
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by ChEMBL
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by ChEMBL
Affinity DataKi: 0.720nMAssay Description:Displacement of [3H]MDL from rat 5HT2A receptor expressed in GF62 cells by liquid scintillation analyserMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by ChEMBL
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by ChEMBL
Affinity DataKi: 53nMAssay Description:Inhibition of human cloned 5-HT2C receptor by competitive binding experimentMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by ChEMBL
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by ChEMBL
Affinity DataKi: 59nMAssay Description:Inhibition of human cloned 5HT7 receptor by competitive binding experimentMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by ChEMBL
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by ChEMBL
Affinity DataKi: 71nMAssay Description:Binding affinity to human 5-HT2C assessed as inhibition constantMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by ChEMBL
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by ChEMBL
Affinity DataKi: 320nMAssay Description:Inhibition of human cloned 5HT2B receptor by competitive binding experimentMore data for this Ligand-Target Pair
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by ChEMBL
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by ChEMBL
Affinity DataKi: 335nMAssay Description:Inhibition of human cloned alpha1A adrenergic receptor by competitive binding experimentMore data for this Ligand-Target Pair
TargetD(4) dopamine receptor(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by ChEMBL
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by ChEMBL
Affinity DataKi: 442nMAssay Description:Inhibition of human cloned dopamine D4 receptor by competitive binding experimentMore data for this Ligand-Target Pair
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by ChEMBL
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by ChEMBL
Affinity DataKi: 500nMAssay Description:Inhibition of human cloned alpha1B adrenergic receptor by competitive binding experimentMore data for this Ligand-Target Pair
TargetHistamine H1 receptor(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by ChEMBL
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by ChEMBL
Affinity DataKi: 509nMAssay Description:Inhibition of human cloned histamine H1 receptor by competitive binding experimentMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by ChEMBL
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by ChEMBL
Affinity DataKi: 884nMAssay Description:Inhibition of human cloned 5HT1B receptor by competitive binding experimentMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by ChEMBL
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by ChEMBL
Affinity DataKi: 1.06E+3nMAssay Description:Inhibition of human cloned 5HT1D receptor by competitive binding experimentMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by ChEMBL
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by ChEMBL
Affinity DataKi: 2.21E+3nMAssay Description:Inhibition of human cloned SERT by competitive binding experimentMore data for this Ligand-Target Pair
TargetHistamine H2 receptor(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by ChEMBL
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by ChEMBL
Affinity DataKi: 2.43E+3nMAssay Description:Inhibition of human cloned histamine H2 receptor by competitive binding experimentMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by ChEMBL
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by ChEMBL
Affinity DataKi: 2.69E+3nMAssay Description:Inhibition of human cloned dopamine D2 receptor by competitive binding experimentMore data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by ChEMBL
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by ChEMBL
Affinity DataKi: 3.83E+3nMAssay Description:Inhibition of human cloned dopamine D1 receptor by competitive binding experimentMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by ChEMBL
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by ChEMBL
Affinity DataKi: 3.84E+3nMAssay Description:Inhibition of human cloned 5HT6 receptor by competitive binding experimentMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 5A(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by ChEMBL
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by ChEMBL
Affinity DataKi: 6.81E+3nMAssay Description:Inhibition of human cloned 5HT5A receptor by competitive binding experimentMore data for this Ligand-Target Pair
TargetD(1B) dopamine receptor(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by ChEMBL
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by ChEMBL
Affinity DataKi: 7.42E+3nMAssay Description:Inhibition of human cloned dopamine D5 receptor by competitive binding experimentMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by ChEMBL
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human cloned DAT by competitive binding experimentMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by ChEMBL
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human cloned 5HT3 receptor by competitive binding experimentMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by ChEMBL
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human cloned 5HT1A receptor by competitive binding experimentMore data for this Ligand-Target Pair
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by ChEMBL
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human cloned beta3 adrenergic receptor by competitive binding experimentMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by ChEMBL
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human cloned alpha2A adrenergic receptor by competitive binding experimentMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by ChEMBL
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human cloned mu opioid receptor by competitive binding experimentMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by ChEMBL
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human cloned histamine H3 receptor by competitive binding experimentMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1E(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by ChEMBL
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human cloned 5HT1E receptor by competitive binding experimentMore data for this Ligand-Target Pair