BDBM50267508 4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-fluorophenylethyl)-piperidine::CHEMBL516088

SMILES COc1c(OCCF)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1

InChI Key InChIKey=HVJOIRMQZXEGPW-UHFFFAOYSA-N

Data  26 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 26 hits for monomerid = 50267508   

Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50267508(4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-fl...)
Affinity DataKi:  3.23nMAssay Description:Displacement of [3H]MDL from rat 5HT2A receptor expressed in GF62 cells by liquid scintillation analyserMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50267508(4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-fl...)
Affinity DataKi:  128nMAssay Description:Inhibition of human cloned 5-HT2C receptor by competitive binding experimentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50267508(4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-fl...)
Affinity DataKi:  146nMAssay Description:Inhibition of human cloned alpha1A adrenergic receptor by competitive binding experimentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50267508(4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-fl...)
Affinity DataKi:  174nMAssay Description:Inhibition of human cloned dopamine D4 receptor by competitive binding experimentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50267508(4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-fl...)
Affinity DataKi:  210nMAssay Description:Inhibition of human cloned 5HT7 receptor by competitive binding experimentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50267508(4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-fl...)
Affinity DataKi:  333nMAssay Description:Inhibition of human cloned alpha2C adrenergic receptor by competitive binding experimentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50267508(4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-fl...)
Affinity DataKi:  550nMAssay Description:Inhibition of human cloned alpha1B adrenergic receptor by competitive binding experimentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50267508(4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-fl...)
Affinity DataKi:  713nMAssay Description:Inhibition of human cloned 5HT1D receptor by competitive binding experimentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50267508(4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-fl...)
Affinity DataKi:  863nMAssay Description:Inhibition of human cloned alpha2A adrenergic receptor by competitive binding experimentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50267508(4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-fl...)
Affinity DataKi:  944nMAssay Description:Inhibition of human cloned histamine H1 receptor by competitive binding experimentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50267508(4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-fl...)
Affinity DataKi:  960nMAssay Description:Inhibition of human cloned 5HT2B receptor by competitive binding experimentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50267508(4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-fl...)
Affinity DataKi:  1.41E+3nMAssay Description:Inhibition of human cloned dopamine D1 receptor by competitive binding experimentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 5A(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50267508(4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-fl...)
Affinity DataKi:  1.58E+3nMAssay Description:Inhibition of human cloned 5HT5A receptor by competitive binding experimentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50267508(4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-fl...)
Affinity DataKi:  1.68E+3nMAssay Description:Inhibition of human cloned 5HT1A receptor by competitive binding experimentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H2 receptor(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50267508(4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-fl...)
Affinity DataKi:  1.76E+3nMAssay Description:Inhibition of human cloned histamine H2 receptor by competitive binding experimentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50267508(4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-fl...)
Affinity DataKi:  2.17E+3nMAssay Description:Inhibition of human cloned 5HT1B receptor by competitive binding experimentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50267508(4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-fl...)
Affinity DataKi:  3.09E+3nMAssay Description:Inhibition of human cloned SERT by competitive binding experimentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50267508(4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-fl...)
Affinity DataKi:  3.83E+3nMAssay Description:Inhibition of human cloned dopamine D2 receptor by competitive binding experimentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1B) dopamine receptor(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50267508(4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-fl...)
Affinity DataKi:  7.40E+3nMAssay Description:Inhibition of human cloned dopamine D5 receptor by competitive binding experimentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50267508(4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-fl...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human cloned 5HT6 receptor by competitive binding experimentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50267508(4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-fl...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human cloned histamine H3 receptor by competitive binding experimentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50267508(4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-fl...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human cloned beta3 adrenergic receptor by competitive binding experimentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50267508(4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-fl...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human cloned mu opioid receptor by competitive binding experimentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50267508(4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-fl...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human cloned DAT by competitive binding experimentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1E(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50267508(4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-fl...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human cloned 5HT1E receptor by competitive binding experimentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50267508(4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-fl...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human cloned 5HT3 receptor by competitive binding experimentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed