BDBM50267813 (4Z)-4-{[(4-Hydroxybenzyl)amino]methylene}isoquinoline-1,3(2H,4H)-dione::CHEMBL489627

SMILES Oc1ccc(CNC=C2C(=O)NC(=O)c3ccccc23)cc1

InChI Key InChIKey=YUSZALWWAUHWNF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50267813   

TargetCyclin-dependent kinase 2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50267813((4Z)-4-{[(4-Hydroxybenzyl)amino]methylene}isoquino...)
Affinity DataIC50: 1.73E+4nMAssay Description:Inhibition of CDK2/Cyclin E assessed as inhibition of retinoblastoma susceptibility gene product phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50267813((4Z)-4-{[(4-Hydroxybenzyl)amino]methylene}isoquino...)
Affinity DataIC50: 3.72E+4nMAssay Description:Inhibition of CDK1/Cyclin B1 assessed as inhibition of retinoblastoma susceptibility gene product phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50267813((4Z)-4-{[(4-Hydroxybenzyl)amino]methylene}isoquino...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CDK4/Cyclin D1 assessed as inhibition of retinoblastoma susceptibility gene product phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed