BDBM50267816 4-{[2-(3,4-Dihydroxy-phenyl)-ethylamino]-methylene}-4H-isoquinoline-1,3-dione::CHEMBL489431

SMILES Oc1ccc(CCNC=C2C(=O)NC(=O)c3ccccc23)cc1O

InChI Key InChIKey=YGRPGFBUNPPGAB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50267816   

TargetCyclin-dependent kinase 4(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50267816(4-{[2-(3,4-Dihydroxy-phenyl)-ethylamino]-methylene...)
Affinity DataIC50: 1.62E+4nMAssay Description:Inhibition of CDK4/Cyclin D1 assessed as inhibition of retinoblastoma susceptibility gene product phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed