BDBM50270005 5'-(N-ethyl-N-isopropyl)amiloride::CHEMBL1909809::CHEMBL517986::cid_1795

SMILES CCN(C(C)C)c1nc(N)c(nc1Cl)C(=O)NC(N)=N

InChI Key InChIKey=QDERNBXNXJCIQK-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50270005   

TargetDelta-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50270005(5'-(N-ethyl-N-isopropyl)amiloride | CHEMBL1909809 ...)
Affinity DataEC50:  6.41E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University Of Wollongong

Curated by ChEMBL
LigandPNGBDBM50270005(5'-(N-ethyl-N-isopropyl)amiloride | CHEMBL1909809 ...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of urokinase-type plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50270005(5'-(N-ethyl-N-isopropyl)amiloride | CHEMBL1909809 ...)
Affinity DataIC50:  800nMAssay Description:Inhibition of human wild type NHE1 expressed in chinese hamster AP1 cells assessed as intracellular pHi recovery by ammonium chloride prepulse protoc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger(Amphiuma tridactylum)
University Of California

Curated by ChEMBL
LigandPNGBDBM50270005(5'-(N-ethyl-N-isopropyl)amiloride | CHEMBL1909809 ...)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibition of Amphiuma tridactylum wild type NHE1 expressed in chinese hamster AP1 cells assessed as intracellular pHi recovery by ammonium chloride ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed