BDBM50095174 3,5-Dimethyl-pyrazole-1-carboxamidine; hydrochloride::CHEMBL451397::CHEMBL553974

SMILES Cc1cc(C)n(n1)C(N)=N

InChI Key InChIKey=GAZRNXIMWKZADY-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50095174   

TargetNitric oxide synthase, brain(Human)
Instituto De QuíMica MéDica

Curated by ChEMBL
LigandPNGBDBM50095174(CHEMBL451397 | CHEMBL553974 | 3,5-Dimethyl-pyrazol...)
Affinity DataKi:  3.50E+5nMAssay Description:Inhibition of nNOS assessed as conversion of L-[3H]arginine to L-[3H]citrullineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Rat)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50095174(CHEMBL451397 | CHEMBL553974 | 3,5-Dimethyl-pyrazol...)
Affinity DataKi:  3.50E+5nMAssay Description:Time dependent inhibition against neuronal Nitric Oxide Synthase(nNOS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50095174(CHEMBL451397 | CHEMBL553974 | 3,5-Dimethyl-pyrazol...)
Affinity DataKi:  7.50E+5nMAssay Description:Inhibition against induced Nitric Oxide Synthase(iNOS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50095174(CHEMBL451397 | CHEMBL553974 | 3,5-Dimethyl-pyrazol...)
Affinity DataKi:  1.50E+6nMAssay Description:Inhibition against endothelial Nitric Oxide Synthase(eNOS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed