BDBM50273129 CHEMBL514249::methyl 2-(3-oxo-6-(1-(3,4,5-trifluorophenyl)piperidine-4-carboxamido)-3,4-dihydro-2H-benzo[b][1,4]oxazin-2-yl)acetate

SMILES COC(=O)CC1Oc2ccc(NC(=O)C3CCN(CC3)c3cc(F)cc(F)c3)cc2NC1=O

InChI Key InChIKey=DTCFTICOGRXUIT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50273129   

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50273129(methyl 2-(3-oxo-6-(1-(3,4,5-trifluorophenyl)piperi...)
Affinity DataIC50: 890nMAssay Description:Antagonist activity at human TRPV1 receptor assessed as inhibition of capsaicin-induced calcium flux by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed