BDBM50273209 CHEMBL4126759

SMILES CCn1c(nc2ccccc12)C(=O)N(CC(C)C)[C@@H]1CNC[C@H](CO)C1

InChI Key InChIKey=IKNCOGQNONQASB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50273209   

TargetRenin(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50273209BDBM50273209(CHEMBL4126759)
Affinity DataIC50: 10nMAssay Description:Inhibition of renin in human plasma by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2020
Entry Details Article
PubMed
TargetRenin(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50273209BDBM50273209(CHEMBL4126759)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human renin using angiotensinogen as substrate pretreated for 10 mins followed by substrate addition measured after 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2020
Entry Details Article
PubMed
TargetRenin(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50273209BDBM50273209(CHEMBL4126759)
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant human renin using angiotensinogen as substrate pretreated for 10 mins followed by substrate addition measured after 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2020
Entry Details Article
PubMed