BDBM50273699 (5S,8S,10aR)-N-Benzhydryl-5-((S)-2-(methyl-amino)propanamido)-6-oxo-3-(2-phenyl-acetyl)decahydropyrrolo[1,2-a][1,5]diazocine-8-carboxamide::CHEMBL504559::SM-337

SMILES CN[C@@H](C)C(=O)N[C@H]1CN(CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1)C(=O)Cc1ccccc1

InChI Key InChIKey=YBYZHVZWINISJO-XPSCAIQQSA-N

Data  5 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50273699   

TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50273699((5S,8S,10aR)-N-Benzhydryl-5-((S)-2-(methyl-amino)p...)
Affinity DataKi:  1.30nMAssay Description:Displacement of fluorescent SM5F peptide from His-tagged human cIAP1 BIR3 domain expressed in Escherichia coli BL21(DE3) cells by fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50273699((5S,8S,10aR)-N-Benzhydryl-5-((S)-2-(methyl-amino)p...)
Affinity DataKi:  1.5nMAssay Description:Displacement of fluorescently tagged SM5F from human cIAP-1 BIR3 expressed in Escherichia coli BL21 cells by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 8(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50273699((5S,8S,10aR)-N-Benzhydryl-5-((S)-2-(methyl-amino)p...)
Affinity DataKi:  4.20nMAssay Description:Displacement of fluorescently tagged SM5F from human cIAP-2 BIR3 expressed in Escherichia coli BL21 cells by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 3(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50273699((5S,8S,10aR)-N-Benzhydryl-5-((S)-2-(methyl-amino)p...)
Affinity DataKi:  6.30nMAssay Description:Displacement of fluorescent SM5F peptide from His-tagged human cIAP2 BIR3 domain expressed in Escherichia coli BL21(DE3) cells by fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50273699((5S,8S,10aR)-N-Benzhydryl-5-((S)-2-(methyl-amino)p...)
Affinity DataKi:  111nMAssay Description:Displacement of fluorescent SM5F peptide from His-tagged human XIAP BIR3 domain expressed in Escherichia coli BL21(DE3) cells by fluorescence polariz...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50273699((5S,8S,10aR)-N-Benzhydryl-5-((S)-2-(methyl-amino)p...)
Affinity DataIC50:  370nMAssay Description:Displacement of fluorescent SM5F peptide from His-tagged human XIAP BIR3 domain expressed in Escherichia coli BL21(DE3) cells by fluorescence polariz...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50273699((5S,8S,10aR)-N-Benzhydryl-5-((S)-2-(methyl-amino)p...)
Affinity DataIC50:  9nMAssay Description:Displacement of fluorescent SM5F peptide from His-tagged human cIAP1 BIR3 domain expressed in Escherichia coli BL21(DE3) cells by fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 3(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50273699((5S,8S,10aR)-N-Benzhydryl-5-((S)-2-(methyl-amino)p...)
Affinity DataIC50:  26.3nMAssay Description:Displacement of fluorescent SM5F peptide from His-tagged human cIAP2 BIR3 domain expressed in Escherichia coli BL21(DE3) cells by fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed