BDBM50274022 3-(5-(3-bromobenzylidene)-4-oxo-2-thioxothiazolidin-3-yl)-N-(3-hydroxyphenyl)propanamide::CHEMBL457233

SMILES Oc1cccc(NC(=O)CCN2C(=S)S\C(=C/c3cccc(Br)c3)C2=O)c1

InChI Key InChIKey=XKHYENLXUFEHRD-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50274022   

TargetATP-dependent RNA helicase DDX3X(Human)
Istituto Di Genetica Molecolare

Curated by ChEMBL
LigandPNGBDBM50274022(3-(5-(3-bromobenzylidene)-4-oxo-2-thioxothiazolidi...)
Affinity DataIC50: 9.00E+4nMAssay Description:Inhibition of ATPase activity in human recombinant DDX3 expressed in Escherichia coli by luciferase-based luminescence assay in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetATP-dependent RNA helicase DDX3X(Human)
Istituto Di Genetica Molecolare

Curated by ChEMBL
LigandPNGBDBM50274022(3-(5-(3-bromobenzylidene)-4-oxo-2-thioxothiazolidi...)
Affinity DataKi:  9.00E+4nMAssay Description:Binding affinity to DDX3X (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed