BDBM50274460 CHEMBL504540::FGGFTGARKSARKYANQ::OFQ/N,[Tyr14]

SMILES C[C@H](NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccccc1)[C@@H](C)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)O

InChI Key InChIKey=NTZGMAAQXGNGFH-UHFFFAOYSA-N

Data  2 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50274460   

TargetNociceptin receptor(Mouse)
Mcgill University

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50274460BDBM50274460(CHEMBL504540 | OFQ/N,[Tyr14] | FGGFTGARKSARKYANQ)
Affinity DataKi:  0.00700nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2013
Entry Details
PubMed
TargetNociceptin receptor(Mouse)
Mcgill University

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50274460BDBM50274460(CHEMBL504540 | OFQ/N,[Tyr14] | FGGFTGARKSARKYANQ)
Affinity DataKi:  0.650nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2013
Entry Details
PubMed
TargetNociceptin receptor(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50274460BDBM50274460(CHEMBL504540 | OFQ/N,[Tyr14] | FGGFTGARKSARKYANQ)
Affinity DataIC50: 1.10nMAssay Description:Displacement of [3H]nociceptin from rat ORL1 receptor expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50274460BDBM50274460(CHEMBL504540 | OFQ/N,[Tyr14] | FGGFTGARKSARKYANQ)
Affinity DataEC50:  11nMAssay Description:Activation of rat ORL1 receptor expressed in african green monkey COS7 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed