BDBM50274949 5-(3-(3-methoxybenzyl)pyrrolidin-3-yl)-1H-indole::CHEMBL514759

SMILES COc1cccc(CC2(CCNC2)c2ccc3[nH]ccc3c2)c1

InChI Key InChIKey=NPBACWUTGOBPGG-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50274949   

TargetSodium-dependent noradrenaline transporter(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274949(5-(3-(3-methoxybenzyl)pyrrolidin-3-yl)-1H-indole |...)
Affinity DataKi:  11nMAssay Description:Inhibition of NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274949(5-(3-(3-methoxybenzyl)pyrrolidin-3-yl)-1H-indole |...)
Affinity DataKi:  34nMAssay Description:Inhibition of SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274949(5-(3-(3-methoxybenzyl)pyrrolidin-3-yl)-1H-indole |...)
Affinity DataKi:  39nMAssay Description:Inhibition of DATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274949(5-(3-(3-methoxybenzyl)pyrrolidin-3-yl)-1H-indole |...)
Affinity DataIC50: 100nMAssay Description:Inhibition of CYP2D6 by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed