BDBM50274976 5-(3-benzylpyrrolidin-3-yl)-1H-indole-3-carbonitrile::CHEMBL517305

SMILES N#Cc1c[nH]c2ccc(cc12)C1(Cc2ccccc2)CCNC1

InChI Key InChIKey=GVFNSRVEVUSCRN-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50274976   

TargetSodium-dependent noradrenaline transporter(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274976(5-(3-benzylpyrrolidin-3-yl)-1H-indole-3-carbonitri...)
Affinity DataKi:  5nMAssay Description:Inhibition of NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274976(5-(3-benzylpyrrolidin-3-yl)-1H-indole-3-carbonitri...)
Affinity DataKi:  66nMAssay Description:Inhibition of SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274976(5-(3-benzylpyrrolidin-3-yl)-1H-indole-3-carbonitri...)
Affinity DataKi:  724nMAssay Description:Inhibition of DATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274976(5-(3-benzylpyrrolidin-3-yl)-1H-indole-3-carbonitri...)
Affinity DataIC50: 800nMAssay Description:Inhibition of CYP2D6 by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed