BDBM50277361 4-(pyridin-4-ylmethylamino)-N-(3-(trifluoromethoxy)phenyl)isothiazole-3-carboxamide::CHEMBL475509
SMILES FC(F)(F)Oc1cccc(NC(=O)c2nscc2NCc2ccncc2)c1
InChI Key InChIKey=HPQJCFJZSWQYAT-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50277361
Affinity DataIC50: 260nMAssay Description:Inhibition of VEGFR1 (unknown origin) assessed as blockade of pGAT-biotin phosphorylation in presence of 2 uM ATP by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Inhibition of VEGFR2 (unknown origin) assessed as blockade of pGAT-biotin phosphorylation in presence of 2 uM ATP by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Inhibition of VEGFR2 (unknown origin) expressed in HEK293 cells assessed as inhibition of receptor phosphorylation by ELISAMore data for this Ligand-Target Pair