BDBM50278879 CHEMBL502840::cis-4-(5-(Hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl)pyridin-3-yl)morpholine Sesqui-fumarate

SMILES C1NC[C@@H]2CN(C[C@H]12)c1cncc(c1)N1CCOCC1

InChI Key InChIKey=XYXCOZZITXKLLF-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50278879   

TargetNeuronal acetylcholine receptor subunit alpha-4(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50278879(cis-4-(5-(Hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl)p...)
Affinity DataKi:  47nMAssay Description:Displacement of [3H]cytisine from alpha4beta2 nicotinic acetylcholine receptor in rat brain minus cerebellum membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50278879(cis-4-(5-(Hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl)p...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]A585539 from alpha7 nicotinic acetylcholine receptor in rat brain minus cerebellum membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed