BDBM50280255 7-Amino-3-{[(S)-1-((R)-2-amino-3-phenyl-propionyl)-pyrrolidine-2-carbonyl]-amino}-2-hydroxy-2-methoxy-heptanoic acid methyl ester; dihydrochloride::BMS-181412::CHEMBL539241

SMILES COC(=O)C(O)(OC)C(CCCCN)NC(=O)[C@@H]1CCCN1C(=O)[C@H](N)Cc1ccccc1

InChI Key InChIKey=GKRKBGYQLRCAHK-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50280255   

TargetProthrombin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50280255(7-Amino-3-{[(S)-1-((R)-2-amino-3-phenyl-propionyl)...)
Affinity DataKi:  1.70nMAssay Description:Overall Inhibitory constant against thrombin was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetProthrombin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50280255(7-Amino-3-{[(S)-1-((R)-2-amino-3-phenyl-propionyl)...)
Affinity DataIC50: 32nMAssay Description:Inhibitory concentration against thrombin when incubated with the compound for 3 minMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article