BDBM50284437 CHEMBL4173409

SMILES CC(Oc1ccnc(Nc2cnn(c2)C2CCN(C)CC2)c1)c1cccc(c1)C(=O)NCc1ccc(C)cc1

InChI Key InChIKey=ZJTRWGZUSIPHTB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50284437   

TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284437(CHEMBL4173409)
Affinity DataIC50:  440nMAssay Description:Inhibition of recombinant human GST-tagged ROS1 expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284437(CHEMBL4173409)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of recombinant human GST-tagged ALK expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed