BDBM50286666 CHEMBL347382::N-hydroxy-N'-[3-methoxy-5-(5-(3,4,5-trimethoxyphenyl)tetrathydrofuran-2-yl)-2-propoxyphenyl]-N-ethyl-N-hydroxyurea

SMILES CCCOc1c(NC(=O)N(O)CC)cc(cc1OC)C1CCC(O1)c1cc(OC)c(OC)c(OC)c1

InChI Key InChIKey=YLGWSTZEZPRBPW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50286666   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50286666(CHEMBL347382 | N-hydroxy-N'-[3-methoxy-5-(5-(3,4,5...)
Affinity DataIC50:  150nMAssay Description:In vitro inhibition of 5-lipoxygenase in RBL-2H3 (Rat basophilic leukaemia) cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50286666(CHEMBL347382 | N-hydroxy-N'-[3-methoxy-5-(5-(3,4,5...)
Affinity DataIC50:  150nMAssay Description:In vitro affinity for human PAF receptor on platelet membranes using [3H]-PAF displacement.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-activating factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286666(CHEMBL347382 | N-hydroxy-N'-[3-methoxy-5-(5-(3,4,5...)
Affinity DataIC50:  8nMAssay Description:In vitro inhibition of 5-lipoxygenase in RBL-2H3 (Rat basophilic leukaemia) cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-activating factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286666(CHEMBL347382 | N-hydroxy-N'-[3-methoxy-5-(5-(3,4,5...)
Affinity DataIC50:  8nMAssay Description:In vitro affinity for human PAF receptor on platelet membranes using [3H]-PAF displacement.More data for this Ligand-Target Pair
In DepthDetails Article