BDBM50287929 1N-[4-cyclopropylmethyl-10,17-dihydroxy-(5R,13R,14R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-yl]-3-(4-methylphenyl)-(E)-2-propenamide::CHEMBL297756

SMILES Cc1ccc(\C=C\C(=O)N[C@@H]2CC[C@@]3(O)[C@H]4Cc5ccc(O)c6O[C@@H]2C3(CCN4CC2CC2)c56)cc1

InChI Key InChIKey=JZKZQHCZPOYVJT-GPBMLUTFSA-N

Data  4 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50287929   

TargetMu-type opioid receptor(GUINEA PIG)
TBA

Curated by ChEMBL
LigandPNGBDBM50287929(1N-[4-cyclopropylmethyl-10,17-dihydroxy-(5R,13R,14...)
Affinity DataKi:  0.230nMAssay Description:Compound was evaluated for binding affinity against [3H]- DAMGO labeled mu opioid receptor in guinea-pig brain homogenate.More data for this Ligand-Target Pair
In DepthDetails Article
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
TBA

Curated by ChEMBL
LigandPNGBDBM50287929(1N-[4-cyclopropylmethyl-10,17-dihydroxy-(5R,13R,14...)
Affinity DataKi:  0.600nMAssay Description:Compound was evaluated for binding affinity against [3H]- bremazocine labeled kappa2 opioid receptor in guinea-pig brain homogenate.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDelta-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287929(1N-[4-cyclopropylmethyl-10,17-dihydroxy-(5R,13R,14...)
Affinity DataKi:  9.60nMAssay Description:Compound was evaluated for binding affinity against [3H]- Cl-DPDPE labeled Opioid receptor delta 1 in guinea-pig brain homogenate.More data for this Ligand-Target Pair
In DepthDetails Article
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
TBA

Curated by ChEMBL
LigandPNGBDBM50287929(1N-[4-cyclopropylmethyl-10,17-dihydroxy-(5R,13R,14...)
Affinity DataKi:  171nMAssay Description:Compound was evaluated for binding affinity against [3H]- bremazocine labeled kappa2 opioid receptor in guinea-pig brain homogenate.More data for this Ligand-Target Pair
In DepthDetails Article
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
TBA

Curated by ChEMBL
LigandPNGBDBM50287929(1N-[4-cyclopropylmethyl-10,17-dihydroxy-(5R,13R,14...)
Affinity DataIC50:  13nMAssay Description:Compound was evaluated for binding affinity against [3H]- bremazocine labeled kappa2 opioid receptor in guinea-pig brain homogenate.More data for this Ligand-Target Pair
In DepthDetails Article
TargetKappa-type opioid receptor(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50287929(1N-[4-cyclopropylmethyl-10,17-dihydroxy-(5R,13R,14...)
Affinity DataIC50:  1.71E+4nMAssay Description:Compound was evaluated for kappa opioid receptor mediated agonistic effect in mouse vas deferens(MVD) preparationsMore data for this Ligand-Target Pair
In DepthDetails Article