BDBM50295759 1-(6-chloroimidazo[2,1-b]thiazol-5-ylsulfonyl)-6-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)-1H-pyrrolo[3,2-b]pyridine::CHEMBL564371

SMILES Clc1nc2sccn2c1S(=O)(=O)n1ccc2ncc(cc12)-c1cnn(c1)C1CCNCC1

InChI Key InChIKey=IHQDEVWBUXDZQZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50295759   

TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50295759(1-(6-chloroimidazo[2,1-b]thiazol-5-ylsulfonyl)-6-(...)
Affinity DataIC50:  9nMAssay Description:Inhibition of human recombinant His-tagged c-Met by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50295759(1-(6-chloroimidazo[2,1-b]thiazol-5-ylsulfonyl)-6-(...)
Affinity DataIC50:  9nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50295759(1-(6-chloroimidazo[2,1-b]thiazol-5-ylsulfonyl)-6-(...)
Affinity DataIC50:  90nMAssay Description:Inhibition of c-Met phosphorylation in human A549 cells after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50295759(1-(6-chloroimidazo[2,1-b]thiazol-5-ylsulfonyl)-6-(...)
Affinity DataIC50:  110nMAssay Description:Inhibition of c-Met phosphorylation in human MKN45 cells after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed