BDBM50296350 (S)-3-(4-(2-(4-(2-(2-chlorophenyl)-2-hydroxyethylamino)-2-oxo-1,2-dihydropyridin-3-yl)-7-methyl-1H-benzo[d]imidazol-5-yl)piperazin-1-yl)propanenitrile::BMS-554417::CHEMBL564417

SMILES Cc1cc(cc2[nH]c(nc12)-c1c(NC[C@@H](O)c2ccccc2Cl)cc[nH]c1=O)N1CCN(CCC#N)CC1

InChI Key InChIKey=SLFIVXXZOYCJGB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50296350   

TargetInsulin receptor(Human)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50296350(BMS-554417 | (S)-3-(4-(2-(4-(2-(2-chlorophenyl)-2-...)
Affinity DataIC50: 51nMAssay Description:Inhibition of insulin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50296350(BMS-554417 | (S)-3-(4-(2-(4-(2-(2-chlorophenyl)-2-...)
Affinity DataIC50: 68nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50296350(BMS-554417 | (S)-3-(4-(2-(4-(2-(2-chlorophenyl)-2-...)
Affinity DataIC50: 94nMAssay Description:Inhibition of FAKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50296350(BMS-554417 | (S)-3-(4-(2-(4-(2-(2-chlorophenyl)-2-...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed