BDBM50300444 2,2-bis(4-fluorophenyl)-N-hydroxyacetamide::CHEMBL573190

SMILES ONC(=O)C(c1ccc(F)cc1)c1ccc(F)cc1

InChI Key InChIKey=HHJNWMNXSDYVHL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50300444   

TargetHistone deacetylase 5(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50300444(2,2-bis(4-fluorophenyl)-N-hydroxyacetamide | CHEMB...)
Affinity DataIC50: 280nMAssay Description:Inhibition of human recombinant N-terminal FLAG-tagged HDAC5 (620-1122) expressed in baculovirus after 10 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50300444(2,2-bis(4-fluorophenyl)-N-hydroxyacetamide | CHEMB...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human recombinant N-terminal FLAG-tagged HDAC4 (612-1034) expressed in baculovirus after 10 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50300444(2,2-bis(4-fluorophenyl)-N-hydroxyacetamide | CHEMB...)
Affinity DataIC50: 1.76E+3nMAssay Description:Inhibition of human recombinant N-terminal FLAG-tagged HDAC7 (438-915) expressed in baculovirus after 10 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed