BDBM50301391 1-[4-(4-methylphenyl)butyl]-alpha,alpha-diphenyl-4-piperdine-methanol::CHEMBL571389

SMILES Cc1ccc(CCCCN2CCC(CC2)C(O)(c2ccccc2)c2ccccc2)cc1

InChI Key InChIKey=VFCNPRIWDSWJIG-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50301391   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
The Schering Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50301391(1-[4-(4-methylphenyl)butyl]-alpha,alpha-diphenyl-4...)
Affinity DataIC50: 396nMAssay Description:Inhibition of human ERG in L929 cells at 10 uM by whole cell patch-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
The Schering Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50301391(1-[4-(4-methylphenyl)butyl]-alpha,alpha-diphenyl-4...)
Affinity DataIC50: 396nMAssay Description:Inhibition of human ERG in L929 cells by whole cell patch-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
The Schering Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50301391(1-[4-(4-methylphenyl)butyl]-alpha,alpha-diphenyl-4...)
Affinity DataKi:  39nMAssay Description:Displacement of [3H]pyrilamine from human recombinant histamine H1 receptor expressed in CHO cell by Betaplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed