BDBM50302464 CHEMBL567110::N-(2-(trifluoromethoxy)benzyl)-6-(3,3,3-trifluoropropoxy)nicotinamide

SMILES FC(F)(F)CCOc1ccc(cn1)C(=O)NCc1ccccc1OC(F)(F)F

InChI Key InChIKey=YQFNCZWCKSSKBX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50302464   

TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302464(N-(2-(trifluoromethoxy)benzyl)-6-(3,3,3-trifluorop...)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of human soluble EHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Rat)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302464(N-(2-(trifluoromethoxy)benzyl)-6-(3,3,3-trifluorop...)
Affinity DataIC50: 6nMAssay Description:Inhibition of rat sEHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302464(N-(2-(trifluoromethoxy)benzyl)-6-(3,3,3-trifluorop...)
Affinity DataIC50: 21nMAssay Description:Inhibition of soluble EH in human HepG2 cells by cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed