BDBM50304205 5-(benzo[d]thiazol-2-yl)-2-(6,7-dimethoxyquinazolin-4-ylamino)phenol::CHEMBL593293

SMILES COc1cc2ncnc(Nc3ccc(cc3O)-c3nc4ccccc4s3)c2cc1OC

InChI Key InChIKey=YJLOLSDWRBWJAG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50304205   

TargetEpidermal growth factor receptor(Human)
4Sc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304205BDBM50304205(5-(benzo[d]thiazol-2-yl)-2-(6,7-dimethoxyquinazoli...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of wild type EGF-R by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetAurora kinase B(Human)
4Sc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304205BDBM50304205(5-(benzo[d]thiazol-2-yl)-2-(6,7-dimethoxyquinazoli...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of Aurora-B by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50304205BDBM50304205(5-(benzo[d]thiazol-2-yl)-2-(6,7-dimethoxyquinazoli...)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of VEGFR2 by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetAurora kinase A(Human)
4Sc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304205BDBM50304205(5-(benzo[d]thiazol-2-yl)-2-(6,7-dimethoxyquinazoli...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Aurora-A by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed