BDBM50304217 CHEMBL593910::N-[4-(Benzo[d]thiazol-2''-yl)-2-methoxyphenyl]-7'-methoxy-6'-[3-(4-methylpiperazin-1-yl)propoxy]quinazolin-4'-amine

SMILES COc1cc(ccc1Nc1ncnc2cc(OC)c(OCCCN3CCN(C)CC3)cc12)-c1nc2ccccc2s1

InChI Key InChIKey=FLGQTDLHJSQLIG-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50304217   

TargetAurora kinase A(Human)
4Sc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304217BDBM50304217(N-[4-(Benzo[d]thiazol-2''-yl)-2-methoxyphenyl]-7'-...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Aurora-A by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetAurora kinase B(Human)
4Sc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304217BDBM50304217(N-[4-(Benzo[d]thiazol-2''-yl)-2-methoxyphenyl]-7'-...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of Aurora-B by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
4Sc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304217BDBM50304217(N-[4-(Benzo[d]thiazol-2''-yl)-2-methoxyphenyl]-7'-...)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of TIE2 by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50304217BDBM50304217(N-[4-(Benzo[d]thiazol-2''-yl)-2-methoxyphenyl]-7'-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDGFRbeta by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
4Sc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304217BDBM50304217(N-[4-(Benzo[d]thiazol-2''-yl)-2-methoxyphenyl]-7'-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of wild type EGF-R by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50304217BDBM50304217(N-[4-(Benzo[d]thiazol-2''-yl)-2-methoxyphenyl]-7'-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ERBB2 by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed