BDBM50306231 4-(2-amino-2-oxoethyl)-1-(2-chlorophenyl)-5-(4-chlorophenyl)-N-(4-methylpyridin-3-yl)-1H-pyrazole-3-carboxamide::CHEMBL595234

SMILES Cc1ccncc1NC(=O)c1nn(c(c1CC(N)=O)-c1ccc(Cl)cc1)-c1ccccc1Cl

InChI Key InChIKey=RXEGFAKFIYJRJK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50306231   

TargetCannabinoid receptor 1(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50306231(4-(2-amino-2-oxoethyl)-1-(2-chlorophenyl)-5-(4-chl...)
Affinity DataIC50:  3nMAssay Description:Antagonist activity at human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940-induced GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50306231(4-(2-amino-2-oxoethyl)-1-(2-chlorophenyl)-5-(4-chl...)
Affinity DataIC50:  0.550nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50306231(4-(2-amino-2-oxoethyl)-1-(2-chlorophenyl)-5-(4-chl...)
Affinity DataIC50:  1.70nMAssay Description:Inverse agonist activity at human CB1 receptor expressed in CHO-K1 cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed