BDBM50306271 1-benzoyl-2,3,9,9a-tetrahydro-1H-benzo[de][1,7]naphthyridin-7(8H)-one::CHEMBL596168

SMILES O=C(N1CCc2cccc3C(=O)NCC1c23)c1ccccc1

InChI Key InChIKey=AEIOPNXCPINKMQ-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50306271   

TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50306271(1-benzoyl-2,3,9,9a-tetrahydro-1H-benzo[de][1,7]nap...)
Affinity DataEC50:  840nMAssay Description:Inhibition of PARP1 in human HeLa cells assessed as inhibition of hydrogen peroxide-induced poly(ADP-ribosyl)ationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50306271(1-benzoyl-2,3,9,9a-tetrahydro-1H-benzo[de][1,7]nap...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human PARP1 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed