BDBM50306288 4-(1-(cyclopropylmethyl)-3-(3-hydroxyphenyl)piperidin-3-yl)-N,N-diethylbenzamide::CHEMBL605293

SMILES CCN(CC)C(=O)c1ccc(cc1)C1(CCCN(CC2CC2)C1)c1cccc(O)c1

InChI Key InChIKey=OKNXWFSWOBEIQA-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50306288   

TargetDelta-type opioid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50306288(4-(1-(cyclopropylmethyl)-3-(3-hydroxyphenyl)piperi...)
Affinity DataKi:  0.800nMAssay Description:Displacement of [125I]diprenorphine from human delta opioid receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50306288(4-(1-(cyclopropylmethyl)-3-(3-hydroxyphenyl)piperi...)
Affinity DataIC50: 7.10nMAssay Description:Antagonist activity at delta opioid receptor by GTPgammaS bunding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50306288(4-(1-(cyclopropylmethyl)-3-(3-hydroxyphenyl)piperi...)
Affinity DataKi:  24nMAssay Description:Displacement of [125I]diprenorphine from human kappa opioid receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50306288(4-(1-(cyclopropylmethyl)-3-(3-hydroxyphenyl)piperi...)
Affinity DataKi:  35nMAssay Description:Displacement of [125I]diprenorphine from human mu opioid receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed