BDBM50307519 1-Methyl-8-{[2-(piperidin-1-yl)ethyl]amino}-4,5-dihydro-1Hpyrazolo[4,3-h]quinazoline-3-carboxamide::CHEMBL608444

SMILES Cn1nc(C(N)=O)c2CCc3cnc(NCCN4CCCCC4)nc3-c12

InChI Key InChIKey=UZVSTORNWGBKAL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50307519   

TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307519BDBM50307519(1-Methyl-8-{[2-(piperidin-1-yl)ethyl]amino}-4,5-di...)
Affinity DataIC50: 2.49E+3nMAssay Description:Inhibition of CDK2/Cyclin AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307519BDBM50307519(1-Methyl-8-{[2-(piperidin-1-yl)ethyl]amino}-4,5-di...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed