BDBM50307526 CHEMBL604092::[8-(Cyclopentylamino)-1-methyl-4,5-dihydro-1H-pyrazolo[4,3-h]quinazolin-3-yl](4-methylpiperazin-1-yl)methanone

SMILES CN1CCN(CC1)C(=O)c1nn(C)c-2c1CCc1cnc(NC3CCCC3)nc-21

InChI Key InChIKey=ATQAEYOXBHLKNV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50307526   

TargetAurora kinase A(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307526BDBM50307526([8-(Cyclopentylamino)-1-methyl-4,5-dihydro-1H-pyra...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307526BDBM50307526([8-(Cyclopentylamino)-1-methyl-4,5-dihydro-1H-pyra...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK2/Cyclin AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed