BDBM50308736 CHEMBL602237::n-Butyl-2-Methyl-5-[4-(methylsulfonyl)phenyl]-1-phenyl-1H-pyrrole-3-acetate

SMILES CCCCOC(=O)Cc1cc(-c2ccc(cc2)S(C)(=O)=O)n(c1C)-c1ccccc1

InChI Key InChIKey=ZPDHNNMTUGUGSV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50308736   

TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50308736(CHEMBL602237 | n-Butyl-2-Methyl-5-[4-(methylsulfon...)
Affinity DataIC50:  8.80E+4nMAssay Description:Inhibition of COX2-dependent PGE2 production in LPS-stimulated mouse J774 cells at 10 uM by RIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50308736(CHEMBL602237 | n-Butyl-2-Methyl-5-[4-(methylsulfon...)
Affinity DataIC50:  8.50E+4nMAssay Description:Inhibition of COX2-dependent PGE2 production in LPS-stimulated mouse J774 cells at 1 uM by RIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Mus musculus)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50308736(CHEMBL602237 | n-Butyl-2-Methyl-5-[4-(methylsulfon...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of COX1-dependent PGE2 production in LPS-stimulated mouse J774 cells by RIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50308736(CHEMBL602237 | n-Butyl-2-Methyl-5-[4-(methylsulfon...)
Affinity DataIC50:  14nMAssay Description:Inhibition of COX2-dependent PGE2 production in LPS-stimulated mouse J774 cells by RIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed