BDBM50309182 4-(2-Amino-5-(2,3-dihydrothieno[3,4-b][1,4]dioxin-5-yl)pyridin-3-yl)benzamide::4-[2-AMINO-5-(2,3-DIHYDROTHIENO[3,4-B][1,4]DIOXIN-5-YL)PYRIDIN-3-YL]BENZAMIDE::CHEMBL602931
SMILES NC(=O)c1ccc(cc1)-c1cc(cnc1N)-c1scc2OCCOc12
InChI Key InChIKey=AWUXFIAHZKNRJF-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50309182
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
The Institute Of Cancer Research
Curated by ChEMBL
The Institute Of Cancer Research
Curated by ChEMBL
Affinity DataIC50: 92nMAssay Description:Inhibition of CHK2 by DELFIA assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
The Institute Of Cancer Research
Curated by ChEMBL
The Institute Of Cancer Research
Curated by ChEMBL
Affinity DataEC50: 5.00E+3nMAssay Description:Inhibition of CHK2 in human HT29 cells assessed as blockade of etoposide-induced DNA damage-activated enzyme phosphorylation by Western blotingMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
The Institute Of Cancer Research
Curated by ChEMBL
The Institute Of Cancer Research
Curated by ChEMBL
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of CHK1 by DELFIA assayMore data for this Ligand-Target Pair