BDBM50310645 (S)-2,3-dichloro-N-(pentan-3-yl)-N-(pyrrolidin-3-yl)benzamide::CHEMBL1080969

SMILES CCC(CC)N([C@H]1CCNC1)C(=O)c1cccc(Cl)c1Cl

InChI Key InChIKey=PMZYRKGBQBCWOA-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50310645   

TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50310645((S)-2,3-dichloro-N-(pentan-3-yl)-N-(pyrrolidin-3-y...)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]5HT from human 5HT transporter expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandPNGBDBM50310645((S)-2,3-dichloro-N-(pentan-3-yl)-N-(pyrrolidin-3-y...)
Affinity DataKi:  37nMAssay Description:Displacement of [3H]noradrenaline from human NET receptor expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50310645((S)-2,3-dichloro-N-(pentan-3-yl)-N-(pyrrolidin-3-y...)
Affinity DataKi:  2.60E+3nMAssay Description:Displacement of [3H]dopamine from human DAT receptor expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandPNGBDBM50310645((S)-2,3-dichloro-N-(pentan-3-yl)-N-(pyrrolidin-3-y...)
Affinity DataIC50: 7.74E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed