BDBM50310651 (S)-2-chloro-N-isobutyl-N-(pyrrolidin-3-yl)-3-(trifluoromethyl)benzamide::CHEMBL1077638

SMILES CC(C)CN([C@H]1CCNC1)C(=O)c1cccc(c1Cl)C(F)(F)F

InChI Key InChIKey=CCXVQWDBHGEOJC-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50310651   

TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50310651((S)-2-chloro-N-isobutyl-N-(pyrrolidin-3-yl)-3-(tri...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]5HT from human 5HT transporter expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandPNGBDBM50310651((S)-2-chloro-N-isobutyl-N-(pyrrolidin-3-yl)-3-(tri...)
Affinity DataKi:  103nMAssay Description:Displacement of [3H]noradrenaline from human NET receptor expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50310651((S)-2-chloro-N-isobutyl-N-(pyrrolidin-3-yl)-3-(tri...)
Affinity DataKi:  2.07E+3nMAssay Description:Displacement of [3H]dopamine from human DAT receptor expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandPNGBDBM50310651((S)-2-chloro-N-isobutyl-N-(pyrrolidin-3-yl)-3-(tri...)
Affinity DataIC50: 4.12E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed