BDBM50312476 CHEMBL1080699::{4-[4-(6-Isopropoxypyridin-3-yl)-5-(4-trifluoromethoxyphenyl)-oxazol-2-ylmethoxy]-2-methylphenoxy}acetic Acid

SMILES CC(C)Oc1ccc(cn1)-c1nc(COc2ccc(OCC(O)=O)c(C)c2)oc1-c1ccc(OC(F)(F)F)cc1

InChI Key InChIKey=DNHZIQUHIDDATB-UHFFFAOYSA-N

Data  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50312476   

TargetPeroxisome proliferator-activated receptor delta(Mouse)
The Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50312476({4-[4-(6-Isopropoxypyridin-3-yl)-5-(4-trifluoromet...)
Affinity DataEC50:  7nMAssay Description:Agonist activity at mouse PPARdelta by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
The Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50312476({4-[4-(6-Isopropoxypyridin-3-yl)-5-(4-trifluoromet...)
Affinity DataEC50:  14nMAssay Description:Agonist activity at human PPARdelta ligand binding domain by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
The Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50312476({4-[4-(6-Isopropoxypyridin-3-yl)-5-(4-trifluoromet...)
Affinity DataEC50:  790nMAssay Description:Agonist activity at human PPARalpha ligand binding domain expressed in human 293T cells co-transfected with Gal4-DBD by luciferase transactivation as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
The Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50312476({4-[4-(6-Isopropoxypyridin-3-yl)-5-(4-trifluoromet...)
Affinity DataEC50:  2.49E+3nMAssay Description:Agonist activity at human PPARdelta ligand binding domain expressed in human 293T cells co-transfected with Gal4-DBD by luciferase transactivation as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
The Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50312476({4-[4-(6-Isopropoxypyridin-3-yl)-5-(4-trifluoromet...)
Affinity DataEC50:  7.00E+4nMAssay Description:Agonist activity at human PPARgamma ligand binding domain expressed in human 293T cells co-transfected with Gal4-DBD by luciferase transactivation as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed