BDBM50312502 2-Ethoxy-3-(4-(5-(4-(trifluoromethyl)phenyl)-4-(4-methoxyphenyl)thiazol-2-yl)methoxyphenyl)propanoic Acid::CHEMBL1079669

SMILES CCOC(Cc1ccc(OCc2nc(c(s2)-c2ccc(cc2)C(F)(F)F)-c2ccc(OC)cc2)cc1)C(O)=O

InChI Key InChIKey=WHYOEMGDHWLQND-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50312502   

TargetPeroxisome proliferator-activated receptor alpha(Human)
The Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312502BDBM50312502(2-Ethoxy-3-(4-(5-(4-(trifluoromethyl)phenyl)-4-(4-...)
Affinity DataEC50:  1.09E+3nMAssay Description:Agonist activity at human PPARalpha ligand binding domain expressed in human 293T cells co-transfected with Gal4-DBD by luciferase transactivation as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
The Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312502BDBM50312502(2-Ethoxy-3-(4-(5-(4-(trifluoromethyl)phenyl)-4-(4-...)
Affinity DataEC50:  1.31E+3nMAssay Description:Agonist activity at human PPARgamma ligand binding domain expressed in human 293T cells co-transfected with Gal4-DBD by luciferase transactivation as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
The Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312502BDBM50312502(2-Ethoxy-3-(4-(5-(4-(trifluoromethyl)phenyl)-4-(4-...)
Affinity DataEC50:  1.87E+3nMAssay Description:Agonist activity at human PPARdelta ligand binding domain expressed in human 293T cells co-transfected with Gal4-DBD by luciferase transactivation as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed