BDBM50312624 CHEMBL1091475::Octanedioic Acid Hydroxyamide-{3-[1-(4-Iodophenyl)-1H-[1,2,3]triazol-4-yl]phenyl}amide
SMILES ONC(=O)CCCCCCC(=O)Nc1cccc(c1)-c1cn(nn1)-c1ccc(I)cc1
InChI Key InChIKey=OEDQYVKPPIYBLX-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50312624
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of HDAC8 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of HDAC3 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 24.6nMAssay Description:Inhibition of HDAC2 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of HDAC1 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by ChEMBL
University Of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 10.7nMAssay Description:Inhibition of HDAC10 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Inhibition of HDAC6 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair