BDBM50313696 CHEMBL1086427::N-(6-chloro-7-fluoro-5-phenyl-1H-indazol-3-yl)butyramide

SMILES CCCC(=O)Nc1n[nH]c2c(F)c(Cl)c(cc12)-c1ccccc1

InChI Key InChIKey=PREQLWGLUIHGJV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50313696   

TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313696(CHEMBL1086427 | N-(6-chloro-7-fluoro-5-phenyl-1H-i...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of Cdk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313696(CHEMBL1086427 | N-(6-chloro-7-fluoro-5-phenyl-1H-i...)
Affinity DataIC50:  3.16E+3nMAssay Description:Inhibition of Cdk2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrotubule-associated protein tau(Rattus norvegicus)
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313696(CHEMBL1086427 | N-(6-chloro-7-fluoro-5-phenyl-1H-i...)
Affinity DataIC50:  250nMAssay Description:Inhibition of Tau phosphorylation in rat cerebral cortex after 120 mins by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313696(CHEMBL1086427 | N-(6-chloro-7-fluoro-5-phenyl-1H-i...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human recombinant GSK3-beta using gamma[33P]-ATP after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed