BDBM50314355 4,6-dihydroxy-2-((1-methyl-4-phenyl-1H-indol-3-yl)methylene)benzofuran-3(2H)-one::CHEMBL1091071

SMILES Cn1cc(\C=C2/Oc3cc(O)cc(O)c3C2=O)c2c(cccc12)-c1ccccc1

InChI Key InChIKey=YBGVHKWNMWSUMT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50314355   

TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314355(4,6-dihydroxy-2-((1-methyl-4-phenyl-1H-indol-3-yl)...)
Affinity DataIC50: 33nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50314355(4,6-dihydroxy-2-((1-methyl-4-phenyl-1H-indol-3-yl)...)
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed