BDBM50315212 1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-6-(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)-1,3,5-triazin-2-yl)phenyl)-3-(4-(4-methylpiperazin-1-yl)phenyl)urea::CHEMBL1088974

SMILES CN1CCN(CC1)c1ccc(NC(=O)Nc2ccc(cc2)-c2nc(nc(n2)N2CC3CCC(C2)O3)N2C3CCC2COC3)cc1

InChI Key InChIKey=BJJWFACJRAPFII-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50315212   

TargetSerine/threonine-protein kinase mTOR(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315212(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-6-(3...)
Affinity DataIC50: 2nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6K-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed