BDBM50315444 4,6-dihydroxy-2-((2-phenyl-1H-indol-3-yl)methylene)benzofuran-3(2H)-one::CHEMBL1089422

SMILES Oc1cc2O\C(=C/c3c([nH]c4ccccc34)-c3ccccc3)C(=O)c2c(O)c1

InChI Key InChIKey=FDZLVAKABOAMEY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50315444   

TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315444(4,6-dihydroxy-2-((2-phenyl-1H-indol-3-yl)methylene...)
Affinity DataIC50: 130nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50315444(4,6-dihydroxy-2-((2-phenyl-1H-indol-3-yl)methylene...)
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50315444(4,6-dihydroxy-2-((2-phenyl-1H-indol-3-yl)methylene...)
Affinity DataIC50: 2.78E+3nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed